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Syphilis in the UK continues to rise, particularly among men who have sex with men. Syphilis has also been diagnosed in white British individuals with no obvious risk factors. Two rapidly emerging social phenomena are likely to be helping the transmission of sexually transmitted infections STIs including syphilis. This article describes an unusual case of primary syphilis presenting with tongue and facial sores, and encourages primary care practitioners to consider testing for STIs including syphilis in individuals with oropharyngeal lesions. Condoms reduce the risk of transmission.